News and publications

CHOI, J., MATHEW, S., OERTER, S., APPELT-MENZEL, A., HANSMANN, J., AND SCHMITZ, T. 2022.
Online Measurement System for Dynamic Flow Bioreactors to Study Barrier Integrity of hiPSC-Based Blood-Brain Barrier In Vitro
Models.
Bioengineering (Basel) 9, 1.

FUHR, A., KURTZ, A., HIEPEN, C., AND MÜLLER, S. 2022.
Organoids as Miniature Twins—Challenges for Comparability and Need for Data Standardization and Access.
Organoids 1, 1, 28–36.

 

KWOK, C.K., SÉBASTIEN, I., HARIHARAN, K., MEISER, I., WIHAN, J., ALTMAIER, S., KARNATZ, I., BAUER, D., FISCHER, B., FEILE, A., CABRERA-SOCORRO, A., RASMUSSEN, M., HOLST, B., NEUBAUER, J.C., CLAUSEN, C., VERFAILLIE, C., EBNETH, A., HANSSON, M., STEEG, R., AND ZIMMERMANN, H. 2022.
Scalable expansion of iPSC and their derivatives across multiple lineages.
Reprod. Toxicol. 112, 23–35.

 

NGO, T.T.T., ROSSBACH, B., SÉBASTIEN, I., NEUBAUER, J.C., KURTZ, A., AND HARIHARAN, K. 2022.
Functional differentiation and scalable production of renal proximal tubular epithelial cells from human pluripotent stem cells in a dynamic culture system.
Cell Prolif., e13190.

 

HASSELMANN, S., HAHN, L., LORSON, T., SCHÄTZLEIN, E., SÉBASTIEN, I., BEUDERT, M., LÜHMANN, T., NEUBAUER, J.C., SEXTL, G., LUXENHOFER, R., AND HEINRICH, D. 2021.
Freeform direct laser writing of versatile topological 3D scaffolds enabled by intrinsic support hydrogel.
Mater.  Horiz. 8, 12, 3334–3344.

 

HEYDARIAN, M., SCHWEINLIN, M., SCHWARZ, T., RAWAL, R., WALLES, H., METZGER, M., RUDEL, T., AND KOZJAK-PAVLOVIC, V. 2021.
Triple co-culture and perfusion bioreactor for studying the interaction between Neisseria gonorrhoeae and neutrophils: A novel 3D tissue model for bacterial infection and immunity.
J. Tissue Eng. 12, 2041731420988802.

 

MEISER, I., MAJER, J., KATSEN-GLOBA, A., SCHULZ, A., SCHMIDT, K., STRACKE, F., KOUTSOURAKI, E., WITT, G., KEMINER, O., PLESS, O., GARDNER, J., CLAUSSEN, C., GRIBBON, P., NEUBAUER, J.C., AND ZIMMERMANN, H. 2021.
Dropletbased vitrification of adherent human induced pluripotent stem cells on alginate microcarrier influenced by adhesion time and matrix elasticity.
Cryobiology 103, 57–69.

 

BERGER, C., BJØRLYKKE, Y., HAHN, L., MÜHLEMANN, M., KRESS, S., WALLES, H., LUXENHOFER, R., RÆDER, H., METZGER, M., AND ZDZIEBLO, D. 2020.
Matrix decoded - A pancreatic extracellular matrix with organ specific cues guiding human iPSC differentiation.
Biomaterials 244, 119766.

 

FEY, C., BETZ, J., ROSENBAUM, C., KRALISCH, D., VIELREICHER, M., FRIEDRICH, O., METZGER, M., AND ZDZIEBLO, D. 2020.
Bacterial nanocellulose as novel carrier for intestinal epithelial cells in drug delivery studies.
Mater. Sci. Eng. C Mater. Biol. Appl. 109, 110613.

 

GINTANT, G., KAUSHIK, E.P., FEASTER, T., STOELZLE-FEIX, S., KANDA, Y., OSADA, T., SMITH, G., CZYSZ, K., KETTENHOFEN, R., LU, H.R., CAI, B., SHI, H., HERRON, T.J., DANG, Q., BURTON, F., PANG, L., TRAEBERT, M., ABASSI, Y., PIERSON, J.B., AND BLINOVA, K. 2020.
Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations.
Regul. Toxicol. Pharmacol. 117, 104756.

 

LAUSCHKE, K., ROSENMAI, A.K., MEISER, I., NEUBAUER, J.C., SCHMIDT, K., RASMUSSEN, M.A., HOLST, B., TAXVIG, C., EMNÉUS, J.K., AND VINGGAARD, A.M. 2020.
A novel human pluripotent stem cell-based assay to predict developmental toxicity.
Arch. Toxicol. 94, 11, 3831–3846.

 

LE HARZIC, R., MEISER, I., NEUBAUER, J.C., RIEMANN, I., SCHIFFER, M., STRACKE, F., AND ZIMMERMANN, H. 2020.
Diffraction-based technology for the monitoring of contraction dynamics in 3D and 2D tissue models.
Biomed. Opt. Express 11, 2, 517.

 

NEUBAUER, J.C., BUR, S., MEISER, I., KURTZ, A., AND ZIMMERMANN, H. 2020.
Naturwissenschaftliche Grundlagen im Kontext einer klinischen Anwendung von humanen induzierten pluripotenten Stammzellen. In Die klinische Anwendung von humanen induzierten pluripotenten Stammzellen.
Ein Stakeholder-Sammelband, S.

 

GERKE, J. TAUPITZ AND C. WIESEMANN,
Eds. Springer Berlin Heidelberg, Berlin, Heidelberg, 19–127

 

SCHWIEGER, J., HAMM, A., GEPP, M.M., SCHULZ, A., HOFFMANN, A., LENARZ, T., AND SCHEPER, V. 2020.
Alginateencapsulated brain-derived neurotrophic factor-overexpressing mesenchymal stem cells are a promising drug delivery system for protection of auditory neurons.
J. Tissue Eng. 11.

 

SHARIATZADEH, M., CHANDRA, A., WILSON, S.L., MCCALL, M.J., MORIZUR, L., LESUEUR, L., CHOSE, O., GEPP, M.M., SCHULZ, A., NEUBAUER, J.C., ZIMMERMANN, H., ABRANCHES, E., MAN, J., O'SHEA, O., STACEY, G., HEWITT, Z., AND WILLIAMS, D.J. 2020.
Distributed automated manufacturing of pluripotent stem cell products. Int. J. Adv.
Manuf. Technol. 106, 3, 1085–1103.

 

WITT, G., KEMINER, O., LEU, J., TANDON, R., MEISER, I., WILLING, A., WINSCHEL, I., ABT, J.-C., BRÄNDL, B., SÉBASTIEN, I., FRIESE, M.A., MÜLLER, F.-J., NEUBAUER, J.C., CLAUSSEN, C., ZIMMERMANN, H., GRIBBON, P., AND PLESS, O. 2020.
An automated and high-throughput-screening compatible pluripotent stem cell-based test platform for developmental and reproductive toxicity assessment of small molecule compounds.
Cell Biol. Toxicol.

 

HÜGL, S., SCHEPER, V., GEPP, M.M., LENARZ, T., RAU, T.S., AND SCHWIEGER, J. 2019.
Coating stability and insertion forces of an alginate-cell-based drug delivery implant system for the inner ear.
J. Mech. Behav. Biomed. Mater. 97, 90–98.

 

MÜLLERS, Y., MEISER, I., STRACKE, F., RIEMANN, I., LAUTENSCHLÄGER, F., NEUBAUER, J.C., AND ZIMMERMANN, H. 2019.
Quantitative analysis of F-actin alterations in adherent human mesenchymal stem cells: Influence of slowfreezing
and vitrification-based cryopreservation.
PLOS ONE 14, 1.

 

SCHEPER, V., HOFFMANN, A., GEPP, M.M., SCHULZ, A., HAMM, A., PANNIER, C., HUBKA, P., LENARZ, T., AND SCHWIEGER, J. 2019.
Stem Cell Based Drug Delivery for Protection of Auditory Neurons in a Guinea Pig Model of Cochlear Implantation.
Front. Cell. Neurosci. 13, 177.

 

SCHULZ, A., GEPP, M.M., STRACKE, F., BRIESEN, H. VON, NEUBAUER, J.C., AND ZIMMERMANN, H. 2019.
Tyramine-conjugated alginate hydrogels as a platform for bioactive scaffolds. Journal of biomedical materials research.
Part A 107, 1, 114–121.

 

SCHULZ, A., GEPP, M.M., STRACKE, F., BRIESEN, H. VON, NEUBAUER, J.C., AND ZIMMERMANN, H. 2019.
Tyramine-conjugated alginate hydrogels as a platform for bioactive scaffolds.
J. Biomed. Mater. Res. A 107, 1, 114–121.

 

SCHWEDHELM, I., ZDZIEBLO, D., APPELT-MENZEL, A., BERGER, C., SCHMITZ, T., SCHULDT, B., FRANKE, A., MÜLLER, F.-J., PLESS, O., SCHWARZ, T., WIEDEMANN, P., WALLES, H., AND HANSMANN, J. 2019.
Automated real-time monitoring of human pluripotent stem cell aggregation in stirred tank reactors.
Sci. Rep. 9, 1, 12297. https://www.nature.com/articles/s41598-019-48814-w#article-info.

 

FISCHER, B., MEIER, A., DEHNE, A., SALHOTRA, A., TRAN, T.A., NEUMANN, S., SCHMIDT, K., MEISER, I., NEUBAUER, J.C., ZIMMERMANN, H., AND GENTILE, L. 2018.
A complete workflow for the differentiation and the dissociation of hiPSC-derived cardiospheres.
Stem Cell Res. 32, 65–72.

 

KAINDL, J., MEISER, I., MAJER, J., SOMMER, A., KRACH, F., KATSEN-GLOBA, A., WINKLER, J., ZIMMERMANN, H., NEUBAUER, J.C., AND WINNER, B. 2018.
Zooming in on Cryopreservation of hiPSCs and Neural Derivatives. A Dual-Center Study Using Adherent Vitrification.
Stem Cells Transl. Med.

 

NEUBAUER, J.C., SÉBASTIEN, I., GERMANN, A., BRIESEN, H. VON, AND ZIMMERMANN, H. 2018.
Towards a Full Automation of the ELISpot Assay for Safe and Parallelized Immunomonitoring.
Methods Mol. Biol. 1808, 237–247.

 

SCHULZ, A., KATSEN-GLOBA, A., HUBER, E.J., MUELLER, S.C., KREINER, A., PÜTZ, N., GEPP, M.M., FISCHER, B., STRACKE, F., BRIESEN, H. VON, NEUBAUER, J.C., AND ZIMMERMANN, H. 2018.
Poly(amidoamine)-alginate hydrogels: directing the behavior of mesenchymal stem cells with charged hydrogel surfaces. Directing the behavior of mesenchymal stem cells with charged hydrogel surfaces.
J. Mater. Sci.: Mater. Med. 29, 7, 105.

Publications in journals

NEUBAUER, J.C., AND GEPP, M.M. 2022.
Biomaterialien — Nachbildung der Stammzellnische in Bioreaktoren.
Biospektrum (Heidelb) 28, 5, 501–503.